As DooGie had told us about, PerfectDisk build 110 is out. Here is the statement from the PerfectDisk blog:
PerfectDisk 10 Build 110 is now available. Various bugs have been fixed, a couple of which I wanted to specifically point out. We addressed a boot time defrag problem on Intel, multi-core, X64 processors running Vista SP2 or Windows Server 2008 SP2. Microsoft introduced this possible crash with Vista/2008 SP2 and has corrected it for Windows 7, but will not be fixing it for Vista or Windows Server 2008. So we created a workaround. We also made a workaround for the latest version of Safeboot, which introduced a problem for PerfectDisk users.
Update from within the program.